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PRP vs. PRF. What's the difference?

PRP and PRF are autologous platelet concentrates. They are constructed from the patient's blood and perspire a serum that is curative for the body. For many years, PRP has been used by specialists for skin rejuvenation, acne treatment, as well as hair blossoming, and the therapy of orthopedic injuries. Not so long ago, the appearance of PRP - the next generation has become a new stage in cosmetic purposes. The names are very similar, but experts distinguish them by some basic features.

PRP and PRF: history, facts, comparison

After numerous breakdowns over the one-time decades, aesthetic medicine has identified two of the most promising areas:

  • PRP regenerative medicine;

  • anti-aging.

Yet, the first variants of platelet concentrates were organized employing anticoagulants (PRP). But gratitude to a current analysis, getting a fluid fraction of PRF has become possible without anticoagulants.

This effect sought to reach the all-natural platelet concentrate (PRF) with the already-known PRP for skin compartment renewal.

Consequently, all platelet concentrates were non-toxic to the cells, demonstrating their high cell survival. As a result, PRP PRF did not show any toxicity. However, skin fibroblast migration (over 350%) was higher with PRF likened to the authority PRP fraction (200% growth). Cell proliferation induction after 5 days was higher with PRF.

Research indicates that PRF offers the best regenerative potential for mortal skin fibroblasts.

Clinical studies on anti-aging facial aesthetics using PRF - platelet concentrates without anticoagulants show potential benefits over PRP.

PRF is a better potent stimulator of fibroblast collagen migration and synthesis than PRP.

The procedure is harmless; has no manifestations of side effects since blood products are obtained from the blood of the person himself, without the addition of anticoagulants or other chemicals. This is a very safe procedure that eliminates the risk of allergies or infections.

What unites them?

The patient's blood is suitable for adherents of "naturalness."

These technologies fit perfectly into the protocols of complex rejuvenation using hardware and other injection techniques, chemical peeling, and thread lifting, as they significantly speed up the rehabilitation period.

What is the distinction between PRP and PRF?

The PRP fraction (used for PRP treatment) differs from the PPP fraction (used for plasmolifting) in that only the PRP fraction contains a sufficiently high concentration of platelets, which secrete factors that stimulate the growth and recovery (rejuvenation) of the body Fabrics.

Using only the correct fraction of PRP near me ("rich" in platelets) can guarantee the maximum effectiveness of restoration of "lost" tissues and hair follicles.

Only double centrifugation allows you to create a sufficiently large concentration of platelets (more than 1,000,000 cells per microliter).

The PRP (platelet-rich) fraction used for PRP therapy always has a reddish tint, distinguishing it from the PPP (platelet-poor) fraction, which has a straw-yellow color.

The reddish color of platelet-rich plasma is unavoidable because platelets are always located in the top layer of centrifuged blood cells during centrifugation. Platelets fall into one layer, with the youngest and lightest erythrocytes (erythrocytes).

It is impossible to separate platelets from the red "blood globules" (erythrocytes).

There are only so many PRP factions. Usually, no more than 1-2 ml. from 10-20 ml. blood.


PRP treatment in cosmetology is a revolutionary way of skin rejuvenation and healing employing purified and platelet-enriched plasma of the patient. With the help of plasma injections, tissue regeneration, cell proliferation, and the production of proteins - elastin and collagen surface.

PRP injection and therapy is a medical procedure to improve the skin's condition by employing the human body's natural resources. Despite its recent appearance in cosmetology, plasma therapy is not a radical innovation, as it has been used in traditional medicine for many years.

Plasmolifting World was founded in 2003 by a group of biomedical researchers as a fast-growing medical company. They are working to develop strategies and tools to accelerate I restore and restore the cells and tissues of the body.

They use exclusively high-quality consumables and equipment that meet all European countries' regulatory requirements.


PRF (platelet-rich fibrin) is a bioproduct obtained from the patient's blood. PRF is a bioactive "patch" derived from blood. Unlike a conventional bandage or patch, PRF is a powerful stimulant for wound healing or tissue defects.



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